ISAT - RA
Terms
undefined, object
copy deck
- What appear to be the key substances in the initiation and continuance of rheumatoid inflammation?
- Pro-inflammatory cytokines, tumor necrosis factor (TNF) and interleukin-1 (IL-1)
- What are the common joints involved at the onset of RA?
- metacarpophalangeal (MCP) joints, wrists, metatarsophalangeal (MTP) joints at onset but any joints can be involved
- RA is associated with higher mortality often due to _____
- respiratory disease, cardiovascular disease or malignancy
- What are the 7 criteria for RA? You need 4 of these to have an official diagnosis of RA.
- Morning stiffness Arthritis of 3 or more joint areas Arthritis of hand joints Symmetric arthritis Rheumatoid nodules Rheumatoid factor Radiographic changes
- In and around the joints for 1 hour or longer before maximal improvement for at least 6 weeks
- morning stiffness
- 3 or more joint areas simultaneously have had soft tissue swelling or effusion for at least 6 weeks
- arthritis of 3 or more joint areas
- 1 or more area(s) swollen in a wrist, MCP or proximal interphalangeal joints for at least 6 weeks
- arthritis of hand joints
- simultaneous involvement of the same joints bilaterally for at least 6 weeks
- symmetric arthritis
- subcutaneous nodules, over bony prominences, extensor surfaces, or in juxta-articular regions
- rheumatoid nodules
- abnormal amounts of serum rheumatoid factor by any method for which the result has been positive in <5% of normal control subjects
- rheumatoid factor
- typica of RA changes on hand and wrist radiographs
- radiographic changes