Drugs Test Three
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- Albert Neimen
- -discovered a way to isolate HCL, the active ingredient in coca used to make cocaine
- Where was Cocaine taken from?
- South America
- What did cocaine do in patent medicines?
- -Acted as topical anesthetic -Constricted blood vassals -Numbing
- What do CNS stimulants do?
- Increase heart rate, brain activity, energy
- Coca Plant
- -Contains active ingredient in cocaine -Used for supplementation, altitude sickness, energy -Commonly chewed
- Halstead
- One of the 1st to use cocaine as a topical anesthetic
- Who suggested using cocaine to overcome morphine addiction?
- Sigmund Freud
- 1885 Park Davis Pharmaceuticals
- -Got patent on cocaine -called "miracle" drug
- When did cocaine become a narcotic?
- 1914 Harrison act
- Freebase
- -Ether+Cocaine+Heat -Rock form, can be smoked -Brings cocaine back to base -Increased HCL
- Crack
- -Baking Soda, Cocaine, Water -Can be smoked
- What neurotransmitters does cocaine mimic?
- Dopamine, Acetylecholine, Serotonin, Epinephrine, Nor epinephrine
- How does cocaine inhibit natural neurotransmitters?
- Cocaine prevents neurotransmitters from returning to the neurons that released them causing a concentration and amplified effect of the neurotransmitter. The body becomes dependent on the drug to produce this high, without it normal levels of dopamine cause user to crash
- Cocaine Abstince Syndrome
- 1. Cocaine Blues- Withdrawal stage, headaches, nausea, sleep disruption. Intense desire to use. May last 1-3 wks 2. Grey Period- Everything is dull, hard to discern color, depression, boredom. Most relapse occurs here. May last several wks 3. Trigger Stage- Begin to normalize. Different stimuli might trigger desire to use. May last months-lifetime
- Which is more powerful, meth or cocaine?
- Meth- can stay high up to 72 hours
- Ephedrine
- Natural stimulant - Amphetamine was created to replace ephedrine as a synthetic drug in 1952
- 1950s Japan and Sweden's methamphetamine addiction program
- 1. Limit # of amphetamines sold 2. limit what they could be used for 3. Education programs 4. Strict penalties for prescribed use 5. Provided treatment at a low cost -America did not provide treatment
- Psuedophedrine
- Used in home meth labs, ephedrine was made a controlled substance in 1994