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Answers from Qbank Cardiovascular

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Mechanism of indomethacin? Used to treat which heart condition?
PG synthesis inhibitor... Used to induce closure of a PDA
Eisenmenger's?
Change from left-to-right shunt
Where is ACE made in the body?
Endothelial cells of pulmonary capillaries
How does hypoxia affect systemic arterioles?
Causes them to dilate
Left parasternal heave?
RVH
T or F? Removing a parallel resistance increases the total resistance.
True
Which syndrome is frequently associated with the ostium primum type of ASD?
Down syndrome
60 y/o cardiology patient - what does S3 indicated?
CHF
Most likely reason for widened pulse pressure?
Arterial hardening due to arteriosclerosis
Initial alteration leading to atherosclerosis?
Injury to endothelial lining
Ductus arteriosus is derived from which aortic arch
6
How does increased stroke volume affect pulse pressure?
Widens it
Biggest pressure drop in the vascular system?
Arterioles
T or F? Loss of arterioles is a long term consequence of HTN..
True
Radiation of the murmur of aortic stenosis?
Neck
Name the disease: erythema migrans, fever, chills, joint pains, AV block
Lyme disease
Rate of an independent ventricular beat?
~40
Prinzmetal's?
Angina due to coronary artery spasm occurring during rest
Adenosine levels in ventricular hypertrophy?
Increased - ATP is being converted to adenosine
Dressler's syndrome?
Autoimmune phenomenon resulting in fibrinous percarditis and chest pain several weeks after a myocardial infection
In acute hemorrhage, which blood vessels are responsible for minimizing the decrease in mean systemic filling pressure?
Veins and venules
Which conditions could cause sharp, stabbing chest pain?
Pericarditis and dissecting aortic aneurysm
MSFP? Normal value?
Mean circulatory filling pressure - 7 mmHg
Sudden excruciating pain between shoulder blades in a patient with hypertension?
Dissection
Describe the murmur of aortic regurgitation?
Diastolic, high pitched, blowing, best heard along the left sternal border
Decreased arterial pressure, increased systemic venous pressure, and a small quiet heart...
Cardiac tamponade
Which arch gives rise to the internal carotid artery?
Arch 3
T or F? ASDs are caused by incomplete adhesion between the septum primum and septum secundum...
T
Which shunt direction causes cyanosis?
Right-to-left
Ostium primum type of ASD results from failure of...?
Of the septum primum to fuse with the endocardial cushions
What is the most common etiologic agent of infective endocarditis in IV drug abusers?
Staph aureus
T or F? Femoral vein is lateral to the artery?
False. Medial
This causes myocarditis and dysmotility of hollow organs, such as the esophagus, colon, and ureter.
Chagas
Sphenopalatine artery is the terminal branch of...?
Maxillary artery
When does the fetal heart start to beat?
4 weeks
Which bug is associated with colon cancer, bacteremia and endocarditis?
Strep bovis
Epicardium aka?
Visceral pericardium
Endomyocardial fibrosis with hypereosinophilia aka?
Loeffler endocarditis
Scattered mesenchymal cells in a prominent myxoid background - this occurs as a single lesion in the left atrium that may intermittently obstruct the mitral valve
Atrial myxoma
Myxoid degeneration of mitral valve leaflets...
Mitral valve prolapse
Monckeberg arteriosclerosis aka?
Medial calcific sclerosis
Which type of pericarditis is associated with post-MI?
Fibrinous and serofibrinous pericarditis
30% of patients with polyarteritis nodosa have which viral infection?
Hep B
Massive dilation of the aortic root with an absence of atherosclerotic vessel lesions strongly suggests...?
Syphilitic aneurysm
Give the disease name for congenital defective LDL receptor?
Familial hypercholesterolemia
Cystic hygromas are a feature of...?
Turner (Webbed neck)
Fragile X is associated with which valvular problem?
Mitral prolapse
Occasional autopsy heart finding in SIDS?
RVH
What % of Down syndrome patients have congenital CV disease?
20%
Leukocytoclastic angiitis is aka?
Hypersensitivity angiitis
Most common cardiac anomaly in Down syndrome?
Endocardial cushion defect
Which defective protein is made in Marfan?
Fibrillin
Polyarteritis nodosa affects which blood vessels?
Small, medium sized muscular arteries
Which antiarrhythmics decrease SA node automaticity, increase AV node refractoriness, and decrease AV nodal conduction velocity?
Type II - Beta blockers
Which antihypertensive can cause dyslipidemia and AV block?
Metoprolol
Captopril - what class of drug?
ACE inhibitor
Most common adverse effect of niacin?
Flushing
Diltiazem - class of drug?
Ca channel blocker
Rate limiting step in cholesterol synthesis?
HMG-CoA ---> Mevalonic acid
Which agents are used as first-line in HOCM?
Beta blockers
This illicit drug blocks NE uptake?
Cocaine
Amlodipine - type of drug?
Ca channel blocker
Beta blockers with intrinsic sympathomimetic activity..?
Acebutolol and pindolol
This agent can control rapid Afib and Aflutter..
Diltiazem
Drug-induced lupus?
QCHIMP drugs
Anti-HTN drug for a pregnant woman?
Methyl-dopa
List the beta 1 (cardioselective) blockers?
A BEAM - acebutolol, betaxolol, esmolol, atenolol, metoprolol
Which Ca channel blocker could exacerbate CHF?
Verapamil
Phentolamine?
Antagonist at alpha-1 and alpha-2 receptors
Which drugs prolong repolarization, widen the QRS, and prolong the QT?
K+-channel blockers
Drug-induced gout?
Thiazide diureticsq
WPW tx?
Ibutilide - Class III
Afib stabilization?
Diltiazem
T or F? Thiazide diuretics decrease the excretion of calcium?
True
Treatment of HTN in a woman with diabetic nephropathy and hyperuricemia?
ACE inhibitor

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