CU Dental pathology Endocrine Hess
Terms
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- GH and prolactin are secreted by the _____ pituitary and are (acidophilic/basophilic)
- anterior; acidophilic
- ACTH, FSH, LH and TSH are secreted by the _____ pituitary and are (acidophilic/basophilic)
- basophilic
- ACTH is a ________troph, TSH is a ______troph, and FSH and LH are ____trophs
- act corticotroph, tsh thyrotroph, fsh and lh gonadotroph
- ADH and oxytosin are released from and produced in the
- posterior pituitary; hypothalamus
- hyperpituitarism are usually caused by an ______ of the ______ lobe of the pituitary
- adenoma; anterior lobe
- adenomas of the pituitary produce an excess of multiple hormones secreted by that part of the pituitary
- false (amost true), usully produces excess of one type of hormone
- pituitary adenomas are present in ___% of autopsied people
- 25%
- GH adenoma before poohberty causes ______; after pooberty ______
- before gigantism; after acromegaly
- cushings disease is an increased production of _____
- glucocorticoids (as happens in hyperproduction of ACTH
- empty sella syndrome is a (hyper/hypo)function of the _______
- hypo pituitiary
- Anterior pitutitary hypofuncion due to postpartum ischemic necrosis
- Sheehan's Syndrome
- most frequesnt cause of hypopituitarism
- non-secretory pituitary adenoma
- abrupt enlargement of a pituitary adenoma due to acuet hemorrhage within the tumor is calld a
- pituitary apoplexy
- ADH oversecretion is most often due to
- ADH producing tumor sucha as a smoall oat cel carcinoma of the lung
- Syndrome that results in renal retention of water with an inablilty to diulte urine
- Syndrome of inappropriate ADH (SIADH)
- ADH undersecretion causes
- you to pee a lot
- Graves disease is (hyper/hypo)secretion of what hormone and is most common in which gender
- hyperthyroidism, female 7:1
- warm skin, sweating, heat intolerance, hyper0motility of GI tract, increased apetite, osteoporisis, iritabitly, fine oily hair
- hyperthyroidism
- what should you do in a thyroid storm (sudden attack of hyperthyroidism)
- stop dental proceedure, give O2, take vitals, give nitroglycerin and call 911
- hashimotos is
- cells are ineffiecient in converting iodine to thyroid hormone so gland compensates by enlarging. Thyroid tissue is replaced by lymphocytescauses primary hypothyroidism
- wide set eyes, coarse facial features, protruding tongue and umbilicus and severe mental retardation (think eric)
- cretinism
- kind of an adult version of cretinsm (lethartgy, cold intolerance, broad face, tongue enlargement, coarse dry hair)
- myxedema
- most common cause of primary (endogenous) hyperthyroidism
- graves disease
- pretibial myxedema (thickening of the skin over legs and dorsal foot), bulging eyes (exopthamos), and thyrotoxicosis
- graves disease
- HLA-DRS is to _____ as HLA DR3 is to _____
- non-specific lyphoid thyroiditis ; graves disease
- most common cause of hypthyroidism in usa
- hashimotos thyroditis
- autoimmune disease in which there is an increased risk of b-cell lymphoma and auitoantibodies anti-thyroglobulin, anti-thyroid, anti-TSH receptor, anti-iodine receptor are present
- hashimotos thyroditis
- orphan annie nuclei
- papillary carcinoma
- prognoisi for papillary carcinoma of the thyroid is ______, anaplastic (undifferentiated) carcinoma of thyroid is _____-
- good bad
- medulary carcinoma can be associated with
- MEN syndrome Iia and IIb (III)
- "cold" nodule on a scan
- follicular carcinoma of the thyroid
- elevated PTH causes
- stones (kidney), moans, (pain_, bones (excessive bone resorption), groans (gi problems, like constipation)
- Stones groans moans and bones refers to what disorder
- primary hyperparathyroidism
- most common cause of secondary hyperparathyroidism
- renal failure
- chvostek's sign
- unilateral spasm in face by tapping on facial nerve
- adrennal cortex secretes __________, _________, and ________
- glucocorticoids (cortisol), Mineralcorticoids (aldosterone), androgens
- cushings disease is an increased production of _____, that cuases adrenal (atrophy/hypertrophy)
- glucocorticoids, (either, depending on whether it is caused by exogenous corticosteroids being administered (atrophy), or ectopic tumor producing ACTH (hyperplasia)
- cushing's syndrome can be caused by adrenal tumor producing cortisol. This causes nodular hyperplasia.
- true; true
- Conn's syndrome is ________ _________ and is due to _______ serum renin
- primary hyperaldosteronism, decreased
- secondary aldosteronism is due to renal ischemia, ediema or nephroticsyndrome and exhibits _______ serum renin
- which two diseases are asssociated with adrenal hypofuncion
- addisions' and waterhous-friderichsen disease
- the rule of tens applies to ___________ which is overproduction of epinephrine, norepinephrine and VMA that causes hypertension
- pheochromocytoma
- Wermer syndrome is commonly called _____ and linked to chromosome ___
- MEN I, 11
- More than one of the following are involved: pituitary, parathyroid, pancreatic islets, adrenal cortex
- MEN I (wermer syndrome)
- Sipple syndrome is calso called ____, and linked to chromosome ___
- MEN II, 10
- MEN Iib (MEN III) is simliar to MEN ___, except it involves skin, and tongue
- IIa