Lab Dx final

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Iron deficiency :Peripheral smear morphology?: microcytic, hypochromic
Iron deficiency :MCV?: low
Iron deficiency :basophilic stippling?: no
Iron deficiency :serum iron?: low
Iron deficiency :TIBC?: high
Iron deficiency :Serum iron/TIBC?: low <10% then definitely iron defic.
Iron deficiency :ferritin?: under 10, iron defic
Iron deficiency :soluble transferrin receptor?: increased
Iron deficiency :absorption site?: duodenum
Beta Thalessemia trait :?: Beta Thalessemia trait
Beta Thalessemia trait :Peripheral smear morphology?: microcytic
Beta Thalessemia trait :MCV?: low
Beta Thalessemia trait :basophilic stippling?: y
Beta Thalessemia trait :Hgb A2 Assay?: positive
Alpha thalessemia trait :?: Alpha thalessemia trait
Alpha thalessemia trait :Peripheral smear morphology?: microcytic
Alpha thalessemia trait :MCV?: low
anemia of chronic disease :?: anemia of chronic disease
anemia of chronic disease :Peripheral smear morphology?: usually normocytic, microcytic (rarely)
anemia of chronic disease :Reticulocyte count?: Low
anemia of chronic disease :MCV?: normal
anemia of chronic disease :serum iron?: low
anemia of chronic disease :TIBC?: high
anemia of chronic disease :Serum iron/TIBC?: >10%
anemia of chronic disease :ferritin?: normalish
anemia of chronic disease :soluble transferrin receptor?: decreased
sideroblastic anemia :?: sideroblastic anemia
sideroblastic anemia :Peripheral smear morphology?: microcytic
sideroblastic anemia :MCV?: low
aplastic anemia :?: aplastic anemia
aplastic anemia :Peripheral smear morphology?: normocytic
aplastic anemia :Reticulocyte count?: Low
aplastic anemia :MCV?: normal
aplastic anemia :Marrow?: hypoplastic
aplastic anemia :platelets?: low
aplastic anemia :PMN's?: low
aplastic anemia :tx?: transplant
pure red cell aplasia :?: pure red cell aplasia
pure red cell aplasia :Peripheral smear morphology?: normocytic
pure red cell aplasia :Reticulocyte count?: stupid low
pure red cell aplasia :MCV?: normal
pure red cell aplasia :platelets?: normal
pure red cell aplasia :PMN's?: normal
pure red cell aplasia :caused by?: dilantin, parvovirus, thymoma, PRCA
pure red cell aplasia :tx?: roids
myelofibrosis :?: myelofibrosis
myelofibrosis :Peripheral smear morphology?: normocytic
myelofibrosis :Reticulocyte count?: Low
myelofibrosis :MCV?: normal
myelofibrosis :Marrow?: fibrosis
myelofibrosis :physcal exam findings?: big ass spleen
myelodysplasia :?: myelodysplasia
myelodysplasia :Peripheral smear morphology?: normocytic
myelodysplasia :Reticulocyte count?: Low
myelodysplasia :MCV?: normal
myelodysplasia :Marrow?: variable
myelodysplasia :iron staining?: ringed sideroblasts
myelophtisic anemia :?: myelophtisic anemia
myelophtisic anemia :Peripheral smear morphology?: normocytic
myelophtisic anemia :Reticulocyte count?: Low
myelophtisic anemia :MCV?: normal
myelophtisic anemia :Marrow?: marrow replacement
B12 deficiency :?: B12 deficiency
B12 deficiency :Peripheral smear morphology?: macrocytic, multilobed polys
B12 deficiency :MCV?: high
B12 deficiency :absorption site?: terminal ileum
B12 deficiency :foods containing nutrient?: meat, animal products
B12 deficiency :serum b12?: low
folate deficiency :?: folate deficiency
folate deficiency :Peripheral smear morphology?: macrocytic, multilobed polys
folate deficiency :MCV?: high
folate deficiency :absorption site?: jejunum
folate deficiency :foods containing nutrient?: veggies
folate deficiency :red cell folate?: low
folate deficiency :serum folate?: low, but easily altered by one meal
Bleeding :?: Bleeding
Bleeding :Reticulocyte count?: High
Hemolytic anemia :?: Hemolytic anemia
Hemolytic anemia :Reticulocyte count?: up
B12 deficiency due to low IF :?: B12 deficiency due to low IF
B12 deficiency due to low IF :schilling?: no radioactive urine, radioactive after IF
Normocytic anemia and low reticulocyte count :?: Normocytic anemia and low reticulocyte count
Normocytic anemia and low reticulocyte count :initial tests?: Do a bone marrow aspirate and biopsy, possibly cytogenetics
Hemolytic anemia :bilirubin?: up (unconjugated)
Hemolytic anemia :LDH?: elevated (nonspecific)
Hemolytic anemia :chromium 51 survival?: decreased
bleeding :bilirubin?: no effect
bleeding :LDH?: no effect
bleeding :chromium 51 survival?: no effect
warm IgG :?: warm IgG
warm IgG :intra or extra-vascular?: extra
warm IgG :haptoglobin?: no effect
warm IgG :rouleaux?: n
cold IgM :?: cold IgM
cold IgM :intra or extra-vascular?: intra
cold IgM :haptoglobin?: low
cold IgM :rouleaux?: y
pseudoerythrocytosis :?: pseudoerythrocytosis
pseudoerythrocytosis :HCT?: up
pseudoerythrocytosis :plasma volume?: down
pseudoerythrocytosis :which cell lines hyperlastic??: none
pseudoerythrocytosis :big spleen??: no
pseudoerythrocytosis :casued by high EPO?: no
2ndary erythrocytosis :?: 2ndary erythrocytosis
2ndary erythrocytosis :HCT?: up
2ndary erythrocytosis :plasma volume?: no effect
2ndary erythrocytosis :which cell lines hyperlastic??: red
2ndary erythrocytosis :big spleen??: no
2ndary erythrocytosis :casued by high EPO?: yes
polycythemia vera :?: polycythemia vera
polycythemia vera :HCT?: up
polycythemia vera :plasma volume?: no effect
polycythemia vera :which cell lines hyperlastic??: red, wbc, platelets
polycythemia vera :big spleen??: yes
polycythemia vera :casued by high EPO?: EPO independent
Pelger Huet :abnormality?: bilobed PMN
May Hegglin :?: May Hegglin
May Hegglin :abnormality?: basophilic inclusions in WBC
chediak Higashi :?: chediak Higashi
chediak Higashi :abnormality?: giant neutrophil granules, faulty lysosmes
Alders :?: Alders
Alders :abnormality?: deep purple granules, mucopolysaccharide disorder
Maroteaux Lamy :?: Maroteaux Lamy
Maroteaux Lamy :abnormality?: Red-violet granules and lymphocyte vacuoles
Erlichiosis :?: Erlichiosis
Erlichiosis :abnormality?: ?? Caused by rickettsia, ticks
Dohle Bodies :?: Dohle Bodies
Dohle Bodies :abnormality?: 1-2 micron oval blue RER fragments
CML :?: CML
CML :Anemia?: no
CML :RBC morphology?: no change
CML :WBC?: >100K
CML :Other cells?: up baso's and eosinos
CML :>5% myelocytes or younger?: Yes
CML :LAP?: low
CML :Marrow?: myeloid hyperplasia, B&E
CML :Splenomegaly?: yes
CML :t(9:22)?: yes
Myelofibrosis :Anemia?: yes
Myelofibrosis :RBC morphology?: teardrop and nucleated
Myelofibrosis :WBC?: maybe up
Myelofibrosis :Other cells?: no change
Myelofibrosis :>5% myelocytes or younger?: possible
Myelofibrosis :LAP?: variable
Myelofibrosis :Splenomegaly?: yes
Myelofibrosis :t(9:22)?: no
Leukemoid :?: Leukemoid
Leukemoid :Anemia?: no
Leukemoid :RBC morphology?: no change
Leukemoid :WBC?: 30-40K
Leukemoid :Other cells?: no change
Leukemoid :>5% myelocytes or younger?: no
Leukemoid :LAP?: high
Leukemoid :Marrow?: myeloid hyperplasia
Leukemoid :Splenomegaly?: no
Leukemoid :t(9:22)?: no
CLL :?: CLL
CLL :abnormal cell type?: B
CLL :CD5+?: yes
Mono :?: Mono
Mono :abnormal cell type?: B
Hairy cell leukemia :?: Hairy cell leukemia
Hairy cell leukemia :abnormal cell type?: B
Hairy cell leukemia :splenomagaly?: fuckin huge
Hairy cell leukemia :CD5+?: no
Hairy cell leukemia :cytopenia type?: pancytopenia (& lymphocytosis)
Hairy cell leukemia :diagnostic test?: tartrate resistant acid phosphatase, TRAP
AML :?: AML
AML :population?: adult
AML :cytopenia type?: neutropenia, also could have elevated WBC (myeloblasts)
ALL :?: ALL
ALL :population?: children
neutropenia :?: neutropenia
neutropenia :1st step in dx of host defense disorder?: WBC and diferential
B cell disorder :?: B cell disorder
B cell disorder :1st step in dx of host defense disorder?: quantitative Ig's
Complement deficiency :?: Complement deficiency
Complement deficiency :1st step in dx of host defense disorder?: CH50, C3, if bad then quantitative C1-9
T cell disorder :?: T cell disorder
T cell disorder :1st step in dx of host defense disorder?: quantitative T and B lymphocytes, skin test to recall antigens
early complement deficiency :?: early complement deficiency
early complement deficiency :infection type?: pyogenic
late complement deficiency :?: late complement deficiency
late complement deficiency :infection type?: neisseria
platelet problem :Physical exam findings?: petechiae
clotting factors :?: clotting factors
clotting factors :Physical exam findings?: echymosis, joint bleeding
vWD :?: vWD
vWD :Physical exam findings?: joint bleeding
vasculitis :?: vasculitis
vasculitis :Physical exam findings?: palpable purpura
XII and XI :?: XII and XI
XII and XI :what activates in PTT?: kaolin
disorder of: XII, XI, IX, VIII, X, V, II, fibrinogen :?: disorder of: XII, XI, IX, VIII, X, V, II, fibrinogen
disorder of: XII, XI, IX, VIII, X, V, II, fibrinogen :which test?: PTT
heparin :?: heparin
heparin :which test?: PTT
Intrinsic pathway :?: Intrinsic pathway
Intrinsic pathway :which test?: PTT
extrinsic pathway :?: extrinsic pathway
extrinsic pathway :which test?: PT
add trhomboplastin to activate VII :?: add trhomboplastin to activate VII
add trhomboplastin to activate VII :which test?: PT
kaolin to activate XII and XI :?: kaolin to activate XII and XI
kaolin to activate XII and XI :which test?: PTT
VII, X, V, II, fibrinogen :?: VII, X, V, II, fibrinogen
VII, X, V, II, fibrinogen :which test?: PT
hemophilia A :?: hemophilia A
hemophilia A :deficiency?: VIII
Hemophilia B :?: Hemophilia B
Hemophilia B :deficiency?: IX (christmas disease....but it's in Jews!)
loose fibrin :?: loose fibrin
loose fibrin :deficiency?: XIII
clotting factors :Vd?: 40 ml/kg
I :?: I
I :vitamin K??: no
I :PT?: yeah (fibrinogen)
I :PTT?: yeah (fibrinogen)
I :made in liver??: yeah (fibrinogen)
I :coumadin effects??: no
I :protein C & S inhibit?: no
II :?: II
II :vitamin K??: yep
II :PT?: yes
II :PTT?: yes
II :made in liver??: yes
II :coumadin effects??: yes
II :protein C & S inhibit?: no
II :cryoprecipitate?: no
II :prothombin complex concentrates?: yes
III :?: III
III :vitamin K??: no
III :PT?: no
III :PTT?: no
III :made in liver??: no
III :coumadin effects??: no
III :protein C & S inhibit?: no
IV :?: IV
IV :vitamin K??: it's friggin calcium
IV :PT?: it's friggin calcium
IV :PTT?: no
IV :made in liver??: no

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