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Adrenergic Pharmacology

Terms

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acebutolol

atenolol

metoprolol

betaxolol 

2nd gen. beta 1 selective blockers

albuterol

salmeterol

terbutaline

metaproterenol 

beta 2 agonists

    tx asthma, premature labor

carvedilol

labetalol 

3rd gen beta blockers

    beta 2 agonist
    Ca Ch. blocker
    alpha antagonist
    inc. NO
    inc. K efflux (hyperpolarize)
   

nadolol

pindolol

propranolol

timolol 

1st gen non-selective beta blockers
alpha-Me-DOPA

block aromatic aa decarboxylase (makes DA)

block DA hydroxylase (makes NE)

alpha-Me-NE  

alpha 2 agonist

    anti hypertensive

    comes as pro-drug alpha-Me-DOPA 

alpha-Me-para-Tyr

block Tyrosine Hydroxylase (RLS of catech. synth)

    tx malignant pheo 

apraclonidine

alpha 2 agonist

    tx OAG

    acts by vasoconstriction, dec aqueous humor 

clonidine

alpha 2 agonist

    anti hypertensive

    diagnostic for pheo. (no effect=positive) 

dobutamine 

beta 1 agonist

    tx cardiogenic shock 

isoproterenol  
non-selective beta agonist
phenoxybenzamine

alpha antagonist (irreversible)

    pheochromocytoma

    *use before a beta blocker! 

phentolamine

alpha antagonist

    pheochromocytoma

    *use before a beta blocker!

phenylephrine 

alpha 1 agonist

    nasal decongestant

    mydriatic 

prazosin

alpha 1 antagonist 

    anti hypertensive 

tamsulosin  

alpha 1 antagonist

    anti hypertensive 

    BPH 

yohimbine 

alpha 2 antagonist

    increases SNS activity 

Deck Info

17

kmcelroy

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