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Anatomy- Plasma Clotting Factors

Terms

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Factor 1
Fibrinogen
Factor 2
prothrombin
Factor 3
Tissue Tromboplastin
Factor 4
Calcium ions
Factor 5
Proaccelerin
Factor 7
Proconvertin
Factor 8
Antihemophilic factor
Factor 9
Plasma thromboplastin component; christmas factor
factor 10
stuart-prower factor
factor 11
plasma thromboplastin antecedent
factor 12
hageman factor
factor 13
fibrin stabilizing factor
Factor 12 is activated by:
Contact of plasma with negative surface
Factor 12 activates
factor 11
Factor 11 activates
factor 9
What are the components of factor 8 complex?
factor 8, activated factor 9, calcium ions (factor 4), platelet phospholipids
factor 8 complex leads where
common pathway
What initiates the extrinsic pathway
Factor 3 (tissue thromboplastin)
factor 3 activates:
factor 7
what does the factor 7 complex consist of
activated factor 7, factor 3, factor 4, tissue phospholipids.
factor 7 complex leads where?
common pathway.
what activates factor 10?
factor 7 complex, or factor 8 complex.
what does teh factor 5 complex consist of?
activated factor 10, factor 5, factor 4, and either platelet or tissue phosphlipids.
factor 5 complex converts?
inactive factor 2 to active factor 2 (prothrombin to thrombin)
active factor 2 (thrombin) converts...
Factor 1 (fibrinogen) into fibrin monomers.
Active factor 2 (thrombin) activates.
factor 13 (fibrin stabilizing factor)
Factor 13 does what
polymerizes teh fibrin monomers into long insoluble fibrin threads
Function of factor 1:
converted to fibrin
function of factor 2
enzyme
function factor 3
cofactor
function factor 4
cofactor
function factor 5
cofactor
function factor 7
enzyme
function factor 8
cofactor
function factor 9
enzyme
function factor 10
enzyme
function factor 11
enzyme
function factor 12
enzyme
function factor 13
enzyme
pathway factor 1
common
pathway factor 2
common
pathway factor 3
extrinsic
pathway factor 4
intrinsic extrinsic common
pathway factor 5
common
pathway factor 7
extrinsic
pathway factor 8
intrinsic
pathway factor 9
intrinsic
pathway factor 10
common
pathway factor 11
intrinsic
pathway factor 12
intrinsic
pathway factor 13
common

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