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Biochemistry I

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How is ATP formed?
catabolic pathways by phosphorylation of ADO
Starge forms of excess energy from diet
fatty acids and glucose
four hormones that oppose the action of insulin
1.glucagon
2.epinephrine
3.cortisol
4.growth hormone
three major target tissues for insulin
liver, muscle, adipose
insulin promotes glycogen synthesis in these two places
liver and muscle
two tissues that are insensitive to insulin
brain and RBCs
target tissues for glucagon and epinephrine
liver, muscle, adipose
RBC Well-fed state and fast state
glucose uptake, glycolysis, lactate recycled to liver
Brain Well-fed and fast state
glucose uptake, glycolysis, ATP formed
Liver well-fed state
glucose uptake, fills glycogen stores, FA synthesis, VLDLs into blood
Liver fasting
gluconeogenesis, glycogenolysis, ketone body formation
Adipose well-fed
FA uptake, lipoprotein lipase, triglyceride synthesis
Adipose fasting
hormone-sensitive lipase, FA released

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