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ch 13 bio psych

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aquaporins
channels spanning cell membrane that conduct water molecules into/out of cell
what 2 parts can the extracellular compartment of a cell be divided into?
interstitial fluid (fluid between cells) and blood plasma
what is the motive force behind osmosis?
constant vibration and movement of the molecules
adipsia
refusal to drink
what happens if the concentrations of molecules in body fluids is altered the smallest amount?
basic cellular functions stop working properly and animal will die
what is the basic thermoregulatory system made up of?
receptors in skin, body core, hypothalamus detects/transmits info to 2 neural regions: spine, brainstem, hypothalamus
hypertonic
a solution with more salt than normal
what are the 5 hormones involved in appetite?
insulin, leptin, ghrelin, obestatin, PYY3-36
diffusion
tendency for molecules to move down the concentration gradient (from high concen. to low concen.)
osmosis
passive movement of molecules from one place to another
what 3 categories can the behavioural thermoregulatory responses of ecto/endotherms be divided into?
changing exposure of body surface, changing external insulation, selecting surroudings less thermally stressful
hypotonic
solution with less salt than normal
ectotherms
get most of their heat from the environment
arcuate nucleus
in hypothalamus which is implicated to appetite control
set point
the desired value of the system
dehydration
excessive loss of water
osmosensory neuron
measures the movment of water in/out of intracellular compartment
what is the most efficient temp. for enzyme systems?
37 degrees celsius
osmotic pressure
force that pushes/pulls water across the membrane to equalize the concentration of a solute in a solution
at what rate do animals lose heat?
directly proportional to ratio of its surface area to its volume or weight (small animals lose heat faster so must eat more)
what are the 2 key features of osmosensory neurons?
they are stretchy; they use mechanically gated ion channels that open/close when cell is physically deformed
what is adipose tissue formed from?
fat used as long term storage
what 3 sequential mechanisms stimulate insulin release? what are these stages called?
sensory stimuli from food (cephalic phase), during digestion (digestive phase), when glucose enters bloodstream (absorptive phase)
what are the 6 methods we have tried in order to gain control over obesity?
appetite control, increased metabolism, inhibition of fat tissue, reduced absorption, reduced reward, anti-obesity surgery
osmolality
concetration of solute in a solution
osmotic thirst
desire to ingest fluids resulting from excessive loss of water from extracellular compartment; no volume change but high concentration of solute
negative feedback
some of the output system feeds back to reduce the effect of input signals
what does a defect in leptin production cause?
false underreporting of body fat causing animals to overeat
what are the 2 different types of thermoregulation? where in the brain does this happen?
behavioural regulation in lateral hypothalamus/ physiological regulation in preoptic area
what are the 3 basic ways our body uses food for energy?
basal metabolism, active behavioural processes, digestion of food
what is a more conspicious way of generating heat?
shivering; happens when body temp. drops below 36 degrees
what is the pathway for information about glucose levels?
liver via vagus nerve -->nucleus of the solitary tract in brainstem-->hypothalamus
what hormones get released from hypovolemia? what do they do?
vasopressin; contriction of blood vessels and renin; triggers formation of angiotensin 2
endotherms
generate most of their heat through internal processes
what do lesions in the ventromedial hypothalamus cause?
obesity in rats
what happens if ghrelin is unresponsive to feeding?
promts continual hunger
kilocalorie
measure of energy commonly applied to food (quantity of heat require to raise the temp by 1 degree)
what is the rate of chemical reactions dependant one?
temperature
homeostatic
active process of maintaining a particular physiological parameter relavtively constant
trophic factor
substance promoting cell growth and survival
through what process do endotherms generate their heat?
through the breakdown of food aka metabolism
Maudsley therapy
parent-led refeeding of an anorexic person as treatment
glucose transporter
molecule that spans external membrane of cell and transports glucose molecules from outside the cell to inside for use
nutrients
chemicals that are no used as sources of energy but required for effective functioning of the body
what brain area is most sensitive to angiotensin II? what general part of the brain does this specfic area belong to?
subfornical organ; circumventricular organs (in cerebral ventricle)
where do the NPY/AgRP neurons project to in the brain? what do they release? where do the POMC/CART neurons project to in brain?
lateral hypothalamus and release alpha-MSH (decrease feeding); Paraventricular nucleus and LH (increase feeding)
what does obestatin do?
works to decrease appetite
glycogen
a more complicated molecule than glucose which is stored as reserve fuel; process of conversion called glycogenisis
what does PYY3-36 do?
is a potent appetite suppressing stimulus to the hypothalamus
hypovolemic thirst
desire to ingest fluids stimulated by reduced volume of extracellular fluid (blood); loss of volume but same concentration of solute
isotonic
a solution with the same concentration of salt as mammallian fluids have
brown fat
brown adipose tissue found around vital organs in trunk and around cervical/thoracic levels of spinal cord; full of mitochondria that break down molecules and produce heat
waht do lesions in the lateral hypothalamus cause?
aphagia (refusal to eat)
what are the advantages to endothermy? (3)
greater independance from environmental conditions, greater capacity for oxygen utilization leading to high levels of muscular activity
semipermeable membrane
some molecules can pass through it but not all types of molecules
what 2 combo's of peptide neurons does the arcuate nucleus produce?what does each do?
NPY/AgRP neurons:stimulate appetite and reduce metabolism; and POMC/CART neurons: inhibit appetite an dincrease metabolism
glycolysis
conversion of glycogen back into glucose
what are the 3 primary acts of insulin?
promotes glucose as primary energy source, promotes conversion of bloodborne fuels to storable forms, promotes storage of energy sources
baroreceptors
located in majore blood vessels/heart that detect a drop in extracellular volume (pressure receptors)
redundancy
an important process that is monitored and regulated by more than one mechanism
angiotensin II has what water conserving actions?
constricts blood vessels, increases blood pressure, triggers relase of aldosterone which aids in water retention
ketones
metabolic fuel source by breakdown of body fats/proteins
hyperphagia
excessive eating
set zone
range of a variable that the system maintains
what is the difference between set zones in the lower regions of nervous system compared to higher regions?
set zones broader in lower regions, set zones narrowest in highest level (the hypothalamus)
metabolism
breaking of checmical bonds in food which releases energy as heat
glucose
principle sugar used by body for energy; fuels the brain

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