USMLE VIROLOGY
Terms
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- DNA viruses
-
HHAPPPy viruses!
Herpes
Hepadna
Adeno
Papova
Parvo
Pox - adenovirus basics
-
linear dsDNA
naked - adenovirus transmission
- resp, ocular secretions
- adenovirus sx
-
acute resp dz (ARD)
conjunctivitis
gastroenteritis - adenovirus vaccine
-
live nonattentuated
oral
used in military - papovaviruses include
-
HPV
BK
JC
PA/PO/VAviruses are all abbreviated! - JC virus causes
-
PML (progressive multifocal leukoencephalopathy)
esp in AIDS pts - herpesvirus basics
-
large dsDNA virus
enveloped - VZV transmission
- resp secretions
- chickenpox incubation
- 2 wks
- varicella vaccine
- live attenuated
- EBV transmission
- saliva, resp secretions
- EBV associations
-
burkitt lymphoma
nasopharyngeal carcinoma
hairy oral leukoplakia (immunocompromised) - oncogene in burkitt lymphoma
- c-myc
- EBV cells on peripheral smear
-
atypical lymphocytes = activated T cells
foamy cytoplasm (Downy cells) - Paul-Bunnell test
- monospot
- blueberry muffin baby
-
deaf baby with hemorrhagic cutaneous lesions
*congenital CMV* - HHV-6
- causes "sixth disease" = roseola = exanthema subitum
- HHV-8
- cofactor in Kaposi sarcoma
- poxviruses include
-
variola (smallpox)
molluscum contagiosum
cowpox - umbilicated wart-like lesions
- molluscum
- hepadnaviruses include
- hepatitis B virus
- parvovirus (B19) basics
- small ssDNA virus
- parvovirus causes
-
erythema infectiosum (fifth dz)
aplastic crisis
hydrops fetalis - picornavirus basics
-
(+)ssRNA
naked - picornaviruses include
-
PERCH on a "peak" (pico)
Polio
ECHO
Rhino
Coxsackie
Hepatitis - poliovirus vaccine(s)
-
live attenuated (oral)
killed - ECHO viruses
-
Enteric Cytopathic Human Orphan
infect GI tract, esp. in summer
aseptic meningitis, fever, rash, enteritis, common cold, hemorrhagic conjunctivitis - coxsackie season
- summer + fall
- coxsackie transmission
-
nasopharyngeal secretions
also fecal-oral - hepatitis A caused by
- enterovirus 72 (picornavirus)
- herpangina
- coxsackie A
- hand-foot-and-mouth dz
- coxsackie A