Micro. Chap 21
Terms
undefined, object
copy deck
- Fleming discovered penicillin while working with ___________.
- Stapholococcus
-
True or False:
Fleming was able to purify the compound. - False
- Chain and Florey successfully isolated ___________. Waksman isolated _____________ from soil bacteria.
-
Penicillin
Streptomycin - Most modern antibiotics come from organisms living in the __________.
- Soil
- In some cases, drugs are modified to produce new traits, these are termed _______-__________.
- Semi-synthetic
- Selective __________ refers to antimicrobials being more harsh on microes than on humans. Why is this?
-
Toxicity
Interferes with processes common to bacterial cells and not human ones. - Toxicity of a drug is expressed through __________ ___________.
- Theraputic index
- High theraputic index = _______ toxic to humans.
- Less
- The therapeutic index is the lowest dose toxic to the patient divided by....
- The dose usually given for treatment.
-
Drugs may kill or inhibit bacterial growth:
Inhibit = Bacterio________
Kill = Bacterio__________ -
Inhibit = Bacteriostatic
Kill = Bacteriocidal - _________ spectrum drugs work on Gram +'s only OR Gram -'s only.
- Narrow
- Broad spectrum drugs work on Gram + and Gram -, but a disadvantage is disruption to the _________ ________ of the body.
- Normal flora