Med-Surg Nursing - 13
Terms
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- allogenic
- in transplantation denotes tissue, particularly stem cells from either bone marrow or blood, that are from the same species but are antigenically distinct
- anergy
- immunodeficient condition characterized by lack of or diminished reaction to an antigen or group of antigens
- antigen
- a substance that elicits an immune response
- autoimmunity
- an inappropriate immune reaction to self-proteins; the immune system no longer differentiates self from nonself with respect to these substances
- autosomal recessive disease
- disorders that result from mutations of two gene pairs (homozygous) on a chromosome
- cell-mediated immunity
- immunity that is initiated through specific antigen recognition by T lymphocytes, macrophages, and natural killer cells
- cytokines
- soluble factors secreted by white blood cells and a variety of other cells in the body that act as messengers among cells of the immune system, endocrine, and nervous systems
- gene therapy
- treatment of genetic disorders by replacing or repairing defective or missing genes with normal genes
- heterozygous
- the presence of one recessive and one dominant allele at a given chromosomal location
- homozygous
- a trait produced by identical or nearly identical alleles at a given chromosomal location
- human leukocyte antigens
- system that consists of a series of linked genes that occur together on the sixth chromosome in humans and is used to assess tissue compatibility
- humoral immunity
- antibody-mediated immunity
- hypersensitivity reaction
- the result of an immune system that is overreactive against foreign antigens or fails to maintain self-tolerance, resulting in tissue damage
- immunocompetence
- the ability of the body's immune system to identify and inactivate or destroy foreign substances
- immunodeficiency
- inadequate protection of the body by the immune system
- immunosuppressive therapy
- therapy that inhibits immune function and is prescribed for patients to treat autoimmune disorders and to prevent transplant rejection; immunosuppression is a serious side effect of cytotoxic drugs used in cancer chemotherapy
- monoclonal antibodies
- homogeneous populations of identical antibody molecules produced by specialized tissue cell culture lines