Pharmacology Final

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What is the classification for Epinephrine?: Sympathomimetic
Beta-Lactam Antibiotics are______and inhibit_______?: Bactericidal, cell wall synthesis
What is the mechanism of action for Accolate?: Leukotrine receptor antagonist
How many inhalations per day is taken of Azmacort?: 12-16 inhalations/day
What are 2 characteristics of parasympatholytics?: Competitive inhibitor of ACH, Inhibits exercise induced asthma
What surfactant is produced outside the patients body?: Exogenous surfactant
Approximately how many cillia are there per cell?: 200
During the Diurnal steroid cycle what gradually rises and falls?: ACTH and Cortisol
Give an extremely potent and common example of a loop diuretic?: Lasix
A serum level of greater than 40-45 ug/ml of theophylline has what effect?: seizures
Vasodialators directly affect relaxation of what?: Vascular smooth muscle
The renal function filters what electrolytes?: Na+, K+, Cl-
Give 3 beta 1 blocking drugs.: Lopressor, Inderal, Corgard
Give the classification of Pirbuterol?: Noncatecholamine
To achieve maximum therapeutic bronchodilation, the optimum serum level of theophylline is_____ug/ml?: 10-20
Name some side effects for Virazole.: Worsening pulmonary condition, cardiovascular instability, rash, conjunctivitis
What is the mode of action for Nondepolarizing agents?: Blocks receptor sites usually reached by acetylocholine through competitive inhibition.
What is the device used in the administration of NebuPent?: Respigard II Nebulizer
What condition is characterized by inflammation in the lungs?: Asthma
What is the antidote for Heparin?: Prolamine
True or False, Aerobid is shorter acting than Azmacort?: False
Name 3 sympathomimetics used in treating cough and colds.: Decongestants, Topical application, Systemic application
Why are Osmotic Diuretics given via IV?: to decrease intracranial or intraocular pressure
What is the dosage for Accolate?: Oral tablet, 20 mg BID
Surface active agents such as Detergents do what to control mucus?: Affect surface tension
What is the indications for Sulfonamides?: Treatment of intestinal infections and UTI's
What is the trade name for Bitolterol?: Tornalate
What are 2 side effects of Loop Diuretic administration.: Hypochloremia and Hypokalemia
Name the classic Xanthine derivative.: Theophylline
What is the classification of Antitussives?: Cough Suppressant
What % saline is a hypertonic solution?: anything above 0.9%
Give the trade names for 5 aerosolized corticosteroids.: Decadron, Beclovent, Azmacort, Aerobid, Flovent
Mucus is comprised of___% H2O and___% mucin?: 95-5
HPA suppression does what to the hypothalmus and pitutary glands?: decreases adrenal production
dopamine: a monoamine neurotransmitter found in the brain and essential for the normal functioning of the central nervous system
What drug is a classic Osmotic diuretic?: Mannitol
Give an example of a angiotensin 2 antagonist drug.: Cozar
What is the recommended dosage for Albuterol?: 2.5 mg TID or 0.5 mls q6h
Antiadrenergic peripheral activity drugs do what to vascular smooth muscle and peripheral resistance?: Relaxes smooth muscle, decreases peripheral resistance
What is the trade name for Trimcinolone Acetonide?: Azmacort
Give 6 physiologic effects of Xanthines.: CNS Stimulation, Skeletal muscle stimulation, bronchodilation, Pulmonary and coronary vasodilation, Cardiac Stimulation, Diuresis.
What is the dosage for Survanta?: 100 mg/kg
What is the indications for Mucomyst?: Thick retained mucoid secretions
What is the maximum number of inhalations for Bechlamethasone?: 12-16 inhalations/day
What is the trade name for Pentamadine?: NebuPent
What is the indication for Terbutaline?: Asthma, Bronchospactic disorders
What health condition increases eosonophils and neutrophils?: Asthma
What is the primary representative Depolarizing drug?: Succinylcholine
What are 3 representative drugs for Antifungal agents?: Amphotericin B, Mystatin, Fluconazole
What is the mode of action for Thiazide Diuretics?: Inhibits Na+ and Cl- reabsorption in the distal tubules
Asthma stimulates and releases chemical mediators from what cells?: Mast
In the sympathetic Branch, what is the neurotransmitter at the ganglionic synapse?: ACH
Antiviral agents include what 3 drugs?: Ribavirin, Acyclovir, AZT
Acute antihypertensive works directly on________and dilates______and ______circulation?: peripheral blood vessles--- arterial--- venous
What is the dosage for Zyflo?: 600 mg QID
What is the MDI dosage for Atrovent?: 36 mcg or (18mcg/puff qid)
How is Exosurf stored and how is it reconstituted?: Powder, 8 ml of sterile water.
What are the 2 trade names for Metaproterenol?: Metaprel--Alupent
Antibiotics work because they inhibit or alter the bacterias ability to do what?: Inhibit of cell wall synthesis, alter cell membrane permeability, inhibit protein synthesis, inhibit Nucleic Acid synthesis
What is the main action of Neuromuscular blocking agents?: Interruption of transmission of nerve impulse at skeletal neuromuscular junction resulting in paralysis
What is the therapeutic range and oal when using theophylline to achieve bronchodialation?: Serum level of 10-20 ug/ml
What is the onset and duration for Depolarizing agents?: Muscle paralysis in 1-1.5 minutes, duration is 10-15 minutes.
What is the onset and duration for Isoproterenol?: Rapid--20 minutes
What mechanism is responsible for propelling debris and foreign materials out of the lower airways?: Mucociliary escalator
What drug is used as a prophylactic and chronic treatment of asthma?: Zyflo
Give the representative drugs that are Antitussives?: Hycodan, Benylin, Tessalon
Antiplatelet agents interfere with what?: the role of platelets
A serum level of less than 5 ug/ml of theophylline has what effect?: no effect
Give 3 clinical uses for theophylline?: Management of asthma and COPD, Treats apnea in premature newborns, CNS stimulents
What is the indications for Erythromycin?: Respiratory, GI, Skin/tissue infections, Mycoplasm, and legionella pneumonia
What is the trade name for Cromyln Sodium?: Intal
What is the classification for Salmeterol?: Long lasting Beta 2 specific Bronchodilator
What is the trade name for Isoproterenol?: Isuprel
Give 3 secretory structures in the upper and lower airways.: Surface epithelial cells, subepithelial cells, submucosal glands.
What is the primary indications for the use of Corticosteroids?: To prevent or reduce inflammation, treatment of severe asthma.
Name 3 indications for Epinephrine.: Acute Bronchospasams--Acute allergic emergencies--Intracardiac stimulant
Give 3 clinical applications for Corticosteroids.: Control of asthma, treatment for bronchospasm, control allergic responses
Name 3 drugs that are strong Alpha, Beta1 and Beta2.: Epinephrine, Racemic Epinephrine, Ephedrine
What drugs would be indicated for shock?: Dopamine, Epinephrine, Isuprel
Antigen-specific IgE binds to what cells?: Mast
What is the route and dosage for Spriva?: DPI 18 mcg, 1 inhalation, QD
What is the recommended dosage for Isotharine?: 0.25-0.5 ml q4h
Give 3 representative drugs that are antiadrenergic central activity drugs.: Aldomet, Catapres, Wytensin
What % saline is an isotonic solution?: 0.9%
What is the Route of Administration for Osmotic Diruetics?: IV
What is the trade name for Levalbuterol?: Xopenex
What is the mechanism of action for Tetracyclines?: Interfere with protein synthesis
What drug is used for the treatment for Pneumocystis carinii pneumonia?: NebuPent
Name an antibiotic that can be inhaled.: Gentamycin
Mast cells release what 3 inflammatory mediators?: Prostaglandins, leukotrines, histamine
What is the indication for Racemic Epinephrine?: Asthma--Croup--Glottic Edema--Post extubation--Stridor
What antiinfective agent is derived from streptomyces and amino sugars?: Aminoglycosides
What route of administration for theophylline is prefered for acute episodes?: IV
What are some effects of antihistamines?: antihistaminic, sedative, anticholinergic
ACTH stimulates the Adrenal cortex to release what?: Corticosteroid
What is the effect of Muscarinic drugs?: Stimulates ACH receptors at the paracympathetic sites.
Where is Exosurf administered in the body?: Instilled directly into the trachea on inspiration
What is the recommended dosage for Xopenex?: 0.63 mg and 1.25 mg q8h
What is the trade name for Albuterol?: Proventil, Ventolin
Is Survanta a natural or synthetic surfactant?: Natural
What is the trade name for Isotharine?: Bronkosol
A serum level of greater than 20 ug/ml of theophylline has what effect?: nausea
List some actions of Corticosteroids.: Stimulates glucose formation, Suppreses inflammatory responces, regulates the rate of protein synthesis, regulates lipid metabolism, controls distribution of fat increases Hb and RBC, maintains skeletal function.
What is the indication for Cipro?: treatment for Pseudomonas in Respiratory system
Name 4 primarily beta 1&2 drugs.: Isoproterenol--Isoetharine--Salbutamol--Terbutaline
Beta 1 blocking drugs do what to Cardiac output and BP?: Lowers it.
The side effects of atropine are "dose related," 0.5 mg or more produces______2 mg or more produces_____?: Dry mouth, Blurred vision, tachycardia and pupil dialation.
What 5 disease states are an indication for sympathomimetic bronchodialators?: Asthma--Acute&Chronic bronchitis--Emphysema--Systic fibrosis--Bronchiectasis.
What Diuretic is used to prevent acute renal failure?: Mannitol
What is the mechanism of action for Fluoroquinolones?: Inhibits Neucleic Acid Synthesis
What are some side effects when taking aerosolized steroids.: Thrush, Candida Albicans.
Give some representative drugs for expectorants.: Potassium Iodide, Guaifenesin
Give 2 representative drugs that are antiadrenergic peripherals.: Catapres, Minipress
Glucocorticoid drugs do what?: raise the overall steroid level in the body
What is the mechanism of action for erythromycin?: Inhibits protein synthesis
What is the recommended dosage for Terbutaline?: 2.5 mg Tablet TID, Inhalation 1-2 mls of 0.1% solution
Give the mechanism of action for Epinephrine.: Mixture of strong Alpha, Beta 1 and Beta 2
What is the representative carbonic anhydrase inhibitor drug?: Diamox
Give 4 Primarily Beta 1&2 Drugs: Isoproterenol Isoetharine Salbutamol Terbutaline
In the Sympathetic Branch, what is the neurotransmitter at the neuroeffector site?: Norepinephrine
Give a representative antiplatelet drug.: Aspirin
What is the indications for Cephalosporins?: Broad-spectrum activity for klebsiella
What must be done when taking oral steroids?: must be weaned off.
What is the chronic therapy dose for theophylline?: 16 mg/kg per 24 hours
Give the drugs and dosages for Combivent.: MDI Ipratropium and Albuterol (2 puffs, qid)
What is the dosage for Pentamidine?: 300 mg via aerosol q4/weeks, (prophylactic) 600 mg qd x 21 days
What is the mechanism of action of Racemic Epinephrine?: Strong alpha, less beta 1 and 2--Relaxes bronchial smooth muscle--Reduces bronchial edema by vasoconstriction.
T/F Antiadrenergic peripheral drugs do not interfere with peripheral sympathetic activity?: False
What is the principle mechanism of action for surfactant?: Lowers alveolar surface tension
Mediator release causes an inflammatory responce and is manifested as what?: Vascular leakage, bronchoconstriction, mucus secretion and mucosal swelling
What is the SVN dosage for Atrovent?: 500 mcg tid or qid
What is used to treat or prevent Pseudomonas aeruginosa?: Inhaled Antibiotics
What is the trade name for Ribavirin?: Virazole
What is the indication for Pulmozyme?: Treatment of cystic fibrosis
Give 3 routes of administration for sympathomimetic drugs.: Inhalation--Oral--Parenteral
What is the typical result when giving Thiazide Diuretics?: Water loss
Activation of T lymphocytes results in production of what?: IgE
What are the indications for Antifungal Agents?: Fungal infections, Candida albicans,Blastomycoses, Aspergillosis
Name 2 catagories of Neuromuscular blockers.: Nondepolarizing agents and Depolarizing agents
What are the indications for aminoglycosides?: for treating gram negative bacilli
what is the recommended dosage for Pirbuterol?: MDI 0.2 mg/puff, 2 puffs/dose Q6h
What are the indications for Tetracyclines?: Mycoplasm pneumonia
Give 2 indications for Metaproterenol.: Asthma, Bronchospastic disorders
What should you not do 24 hours after the administering of a thrombolytic agent?: Stick the patient
What is the recommended dosage for Atropine?: 0.2% (1mg/0.5ml) or 0.25mg/kg TID or QID
Give 3 representative ACE inhibitor drugs.: Lotensin, Capoten, Vasotec
What is the trade name for Dornase Alfa?: Pulmozyme
What must you do after giving a patient a Neuromuscular blocking agent?: Monitor the patient.
Antiviral agents were developed for treatment of what disease?: HIV
What is the route of administration for Metaproterenol?: MDI, Nebulizer, PO
What is the recommended dosage for Bitolterol?: 1.25 mls q8h
Give 3 indications for giving a Neuromuscular blocker.: Facilitate ET Intubation, Muscle paralysis, Facilitate Mechanical Ventilation.
Survanta is a mixture of what 2 substances?: Bovine and DPPC
Name 2 drug names of surfactant.: Exosurf, Survanta
A group of chemicals secreted by the adrenal cortex and are refered to as adrenal cortical hormones are also known as?: corticosteroids
What is the indication for Antituberculosis agents?: treatment of mycobacterium bacillus
Dosages of Theophylline greater than 20 ug/ml can cause what side effects?: Nausea, Cardiac Arrhythmias, Seizures
Angiotensin 2 antagonists inhibits angiotensin by________not by inhibition.: blockade
What are some examples of wetting agents?: Dilutents, Sterile water, Normal saline, hypotonic saline, Hypertonic saline.
What are the indications for the use of sympathomimetic bronchodialators (Adrenergics)?: Relaxation of bronchial smooth muscle to reverse or improve airflow obstruction, ie (COPD)--Reverse Bronchoconstriction.
Give 2 Nicotinic effects.: Stimulates ACH at ganglia and skeletal muscle sites--Causes increase in BP and muscle tremor.
Osmotic Diuretics are not reabsorbed in the?: Tubules
Where do Osmotic Diuretics primarily act?: Proximal tubules
ACE inhibitors interfere with what system?: Angiotensin
In the sympathetic Branch, what is the principle neurotransmitter?: Norepinephrine
Potassium-Sparing Diuretics block what?: Na+ reabsorption
What is the mechanism of action for Isoproterenol?: Strong Beta 1 and Beta 2--Negligible Alpha
Give the action of Pulmozyme?: Decreases the viscosity by breaking down extracellular DNA
What do thrombolytic agents convert plasminogen to?: Plasmin
What is the most common treatment for decreasing intraocular pressure?: Carbonic anhydrase inhibitors
What is the classification for Isoproterenol?: Catecholamine--Powerful bronchodialator
When the hypothalmus is stimulated it releases what?: CRF
Osmotic Diuretics are filtered through?: Glomerulus
Give 4 indications for administering a parasympatholytic?: Used in treatment of bronchitis, COPD, Certain types of Asthma, Blocks the action of Acetylcholine
Acetylcysteine is imcompatable with what antibiotocs?: Ampicillin, Amphotericin B, Erythromycin, tetracycline
Angiotensin receptors are responsible for what?: Vasoconstriction
What is a representative Potassium-Sparing drug?: Aldactone
What is the treatment regimen for patients with TB?: Multiple drug therapy for 6 and 9 months
Give the indications for Albuterol?: Bronchospasm, Asthma
What does TPA stand for?: Tissue Plasminogen Activator
Cephalosporin Second generation, affects what type of bacteria?: gram positive and some gram negative
What is the dosage for Ribavirin?: 20 mg/ml solution, 12-18 hours/day, 3-7 days
The renal function excretes what?: Nigrogenous waste products
What do you not do when handling survanta?: Do not shake it.
What is the indication for Isotharine?: Useful in the treatment of asthma.
Define proteolysis?: Breaking down of proteins.
What aerosolized coritcosteroid has a built in spacer device?: Azmacort
Name 2 Resorcinols.: Metaproterenol--Terbutaline
What is the trade name for Fluoroquinolone?: Cipro
Give 2 trade names for Erythromycin.: Blaxin and Zithromax
What is a representative drug for Sulfonamides?: TMP-SMX
What is the classification for Bitolterol?: Pro-Drug
Give 2 examples of Vasodialators.: Apresoline, Minoxidil
What is the primary action for Isotharine?: Beta 2--Little Beta 1--Slight Alpha
The anti-inflammatory effect of corticosteroids is due to what?: the ability to inhibit the activity of inflammatory cells and mediators of inflammation.
What is the trade name for Salmeterol?: Serevent
What is the dosage for Flunisolide?: BID
Parasympatolytics do 3 things, what are they?: Block parasympathetic activity--Blocks bronchoconstrictive activity--Block secretory glands
Liquifying expectorants are considered____Mucolytics?: true
What is the trade name for Pirbuterol?: Maxair
What are the 2 drugs that make up Advair Diskus?: Fluticasone Propionate and Salmeterol
What are the 2 most popular trade names for Beclamethasone?: Vanceril, Beclovent
What is the mechanism of action for Depolarizing agents?: Stimulates and prolongs depolarizing of the post synaptic receptors.
What representative drugs that are detergents?: Alevaire, Tergemist
What effect does ethyl alcohol have on surface tension?: lowers it
Give a medication that causes proteolysis in mucus.: Dornaise Alpha
What drug is the most popular for disulfide disruption?: Mucomyst
Prophylactic Antiasthmatics work by inhibiting what?: the release of histamines and leukotrines (SRSA)
What surfactant is a protein-free synthetic surfactant?: Exosurf
A serum level of greater than 30 ug/ml of theophylline has what effect?: cardiac arrhythmias
What are the benefits and disadvantages of using Advair Diskus?: Longer lasting but slower onset.
What are the indications for Beta-Lactam Antibiotics?: treatment of infections caused by streptoccal or staphlococcal species, haemophilus influenzae, gonococcal, syphillis
Give the recommended dosage for Salmeterol?: 50 ug BID : MDI 2 puffs
What is the clinical application for Surfactant?: Prevention of IRDS in preemies, prevention of IRDS in Low birth weight infants, rescue treatment of infants with IRDS
The immunologic responce occurs from T lympocytes interacting with what?: an antigen
Mucomyst is also used to counteract what overdose?: Acetaminophen
What is the molecular size delivered for NebuPent?: 1-2 microns
What must a user of aerosolized steroids do after administration?: Must rinse mouth and gargle after use.
What is the representative Thiazide Diuretic drugs?: Hygroton, Diuril
What is the route of administration for Pirbuterol?: MDI, PO
Antiadrenergic central activity drugs do what to the circulatory system?: inhibits vasoconstriction
What is the recommended dosage for Metaproterenol?: MDI 2-3 inhalations q2-4h: Nebulizer: 0.2-0.3 mls of 5% solution q4-6h
Name 3 primarily Alpha drugs.: Norepinephrine--Phenylephrine--Cyclopentamine
The HPA Pathway consists of what 3 organ systems?: Hypothalamus, Pituitary, Adrenal Axis
What is the Chronic Therapy dose for Theophilline?: 16mg/kg per 24 hrs
What is the initial oral dose for theophylline?: 5 mg/kg
Cillia beat approximately__________ times per minute?: 1200-1300
Give the Dosage for Pulmozyme.: 1 ampule (2.5 mg in 2.5 mil solution) qd
What do Loop Diuretics inhibit in the Loop of Henle?: reabsorption of Na+ and Cl-
How would you deliver ethyl alcohol to the patient and what % dose?: SVN 30-50%
What do antihistamine agents target?: H1 receptor antagonists
What 3 ways is exogenous surfactant obtained?: Humans, Animals, Lab synthesis
Cephalosporin, First generation affects what type of bacteria?: gram positive
Name 2 antihypertensive drugs.: Nipride, Nitroglycerine
What route of administration for theophylline is prefered for maintenance therapy?: PO
What is the effect of Xopenex?: Greater bronchodilation
Name 2 Nondepolarizing drugs.: Curare, Pavulon
What are some side effects of Mucomyst?: Bronchopsasm, excessive liquification, stomatitis, nausea
Theophylline is considered a _____________bronchodilator.: Third line
Name 5 characteristics of Saligenins.: Modification of catecholamine, Are beta2 selective, Minimal cardiac effects, Minimal side effects, Longer onset but lasts longer.
How do you prepare a 300 mg dose for NebuPent?: Reconstitute with 6 mls of sterile water
Other than Asthma give some therapeutic uses of steroids.: Bronchitis, arthritis
The term "Cholinergic" refers to what neurotransmitter?: ACH
What is used to treat acute pulmonary edema?: Ethyl Alcohol
From where is Survanta obtained?: Cow lung
What is the classification for Accolate?: Prophylactic Asthmatic
What is the major risk for patients treated with anticoagulants?: Bleeding
What is the andtidote for Coumadin?: Vitamin K
Give 2 representative thrombolytic agent drugs.: Urokinase, Streptokinase, Activase
A serum level of 10-20 ug/ml of theophylline has what effect?: therapeutic
What is the classification for Tetracyclines?: Bacteriostatic, bactericidal
What should be checked 1-2 hours after immediate release from the hospital?: Theophylline levels
NebuPent is what type of agent?: Antiprotozoal
Give the drugs and dosage for DuoNeb.: SVN Ipratropium (0.5 mg) & Albuterol (3.0 mg) tid
Inflammation happens in the body because of what response?: Immunologic (Allergic) Response
What is the indication for Virazole?: RSV, influenza, herpes simplex virus
What 2 sympathomimetics shoud never be given together?: Epinephrine--Isoproterenol
What is the action for Isotharine?: Bronchodialator
What are the 3 types of steroids produced by the adrenal cortex?: Cortisol, aldosterone, testosterone
What is the recommended dosage for Epinephrine?: 0.25-0,5 cc q4h or 4-8 drops q4h
The action of sympathomimetic drugs occurs by stimulation of____located where_____?: Beta 2 receptors--Bronchial smooth muscle
What must you always give before you treat a patient with Mucomyst?: Give a bronchodialator
What is the recommended dosage for Isoproterenol?: 0.25-0.5 ml q3-4h
What is the mechanism of action for Metaproterenol?: Bronchodialation
What is the onset and duration of Nondepolarizing agents?: 1-2 minutes max, effect 2-10 minutes (typical dose 30-60 minutes)
Name 3 drugs that are strong Alpha, Beta1 and Beta 2.: Epinephrine Racemic Epinephrine Ephedrine
What is the recommended dosage for Advair Diskus?: 1 puff BID
What is the trade name of Ipratoprium Bromide?: Atrovent
Accumulation of eosoniphils results in what condition?: Increased airway obstruction
Exosurf is a mixture of what 3 substances?: DPPC, Cetyl alcohol and tloxapol
What is the trade name for Racemic Epinephrine?: Vaponephrine
Cillia are approximately _____Microns in length?: 2-5
Name 4 Catecholamines.: Epinephrine--Isoproterenol--Isoetharine--Racemic Epinephrine
The site of action Parasympatholytics target are?: Central airways, Larger airways
What cycle prepairs the body for stress?: Diurnal Steroid Cycle
What are some indications for surface active agents?: Treatment of pulmonary edema and IRDS
What is the action for Terbutaline?: Bronchodilation
Pure parasympathetic stimulation causes what reaction?: Bronchoconstriction
What are the mechanism of action for expectorants?: Facilitate removal of mucus from lower respiratory tract
Is Exosurf a synthetic or natural surfactant?: Synthetic
What is the dosage for Acetylcysteine?: 10% solution 6-10 ML and 20% solution 3-5 ML
What is the classification for Virazole?: Antiviral
What is the trade name for Flunisolide?: Aerobid
What are some effects that disease has on mucus?: Changes in volume, changes in color, changes in odor, changes in viscosity.
True or False, Systemic steroids have fewer side effects?: False
What are the contraindications for Zyflo?: theophylline and coumadin
What should you monitor while treating a patient with Isuprel and when should you stop giving the treatment?: Patients heart rate--When the patients HR increases 20% past baseline.
Give 2 advantages for giving Bitolterol?: Rapid onset, Long duration
Give 4 representative antihistamine drugs.: Benadryl, Tavist, Seldane, Claritin
What are the effects of Depolarizing agents?: Shorter acting, No antidote.
Name 3 primarily Alpha Drugs: Norepinephrine Phenylephrine Cyclopentamine
What is the indications for Intal?: to prevent asthmatic reactions, prevent exercise-induced bronchospasm and allergic rhinitis.
HPA suppression occurs how?: With exogenous administration of steroids
What molecular size is delivered to the lungs using a SPAG Unit?: 1.3 microns
What is the mechanism of action for Cephalosporins?: inhibition of cell wall synthesis
What is the trade name for Terbubtaline?: Bricanyl, Brethine
How does aminoglycosides affect bacteria?: by distorting and preventing protein synthesis
What are the indications for Theophylline?: Management for asthma and COPD, treat apnea in premature newborns.
What is the classification for Antiviral agents?: Interferons
Antiadrenergic central activity drugs target what receptors in the circulatory system?: Alpha 2
Name some side effects for NebuPent.: Cough, SOB, bad taste, bronchospasm, wheezing, spontaneous pneumothoraces
What do parasympatholytics primarily do?: Block parasympathetic activity
What should you do before giving Isoproterenol?: Get a baseline of HR 100-200 BPM
Vasoconstrictors are used primarily to what?: Support Blood Pressure
Azmacort is____________and has a_______systemic effect?: topically active, minimal
The term "Cholinergic" refers to what neurotransmitter?: ACH
What are the 2 layers of the mucociliary blanket?: Sol & Gel layers
When the Pituitary gland is stimulated it releases what?: ACTH
Name 6 physiologic effects of Xanthines?: CNS stimulation, Skeletal Muscle Stimulation, Bronchodialation, Pulmonary and coronary vasodialation, Cardiac stimulation, Diuresis
What is the initial dose of Theophilline?: 5mg/kg
Name a drug that competitively blocks alpha 1, beta 1 & 2 receptors.: Labetalol
What is the dosage for Exosurf?: 5 ml/kg in 2 divided doses.
The renal function regulates what balance?: Acid base
What are some complicatons of surfactant therapy?: Airway occlusion, bradycardia, desatruation, hyperoxia, hypocarbia, apnea, pulmonary hemorrhage
Cephalosporins third generation, affects what type of bacteria?: expanded gram negative use
Give some side effects for corticosteriods.: Cushing's Disease, Hypertension, Aggravation of diabetes Mellitus, aggravaton of Peptic Ulcers, Psychosis, Adrenal atrophy
Theophylline therapy is considered a__________drug for asthma.: First line
What device is used to deliver Ribavirin?: SPAG unit
what agents are mediators of local inflammatory responses.: Antihistamine agents
what are the side effects of Pulmozyme?: Pharyngitis, laryngitis, rash, chest pain, conjunctivitis
Parasympatholytic Bronchodilators are also known as?: Anticholinergic Agents
What 3 actions cause the lysis of mucus?: Proteolysis, pH Adjustment, disulfide disruption
What was the first available MDI?: Decadron Respihaler
Name 3 common systemic steroids.: Hydrocortisone, Prednisone, Cortisone
Beta adrenergic blockade drugs block beta 1 receptor sites where?: in the heart
What % saline is a hypotonic solution?: 0.45%
What is the route of administration for NebuPent?: inhalation or parenteral

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