pathophysiology coagu. factors
Terms
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- 1
- fibrinogen
- 2
- prothrombin
- 3
- tissue factor (TF) or tissue thromboplastin
- 4
- calcium ions
- 5
-
proaccelerin
labile factor
platelet accelerator - 6
-
# no longer used
substance now believed to be same as factor 5 - 7
-
serum prothrombin conversion accelerator (SPCA)
stable factor - 8
- antihemophilic factor (AHF)
- 9
-
plasma thromboplastin component (PTC)
Christmas factor - 10
-
Stuart factor
Stuart-Prower factor
thrombokinase - 11
- plasma thromboplastin antecedent (PTA)
- 12
-
Hageman factor
glass factor - 13
- fibrin stabilizing factor (FSF)
- erythrocytes
-
4-6 million/mm3
Duration:5-7days
life span:100-120days
transport O2 and CO2 - leukocytes
-
WBC
spherical
nucleated cells
# 4000-11,000 - granulocytes
-
1) neurophil
2) eosinophil
3) basophil - agranulocytes
-
1) lymphocyte
2) monovyte - neutrophil
-
# 3,000-7,000
D: 6-9days
LS: 6 hrs to a few days
phagocytize bacteria - eosinophil
-
# 100-400
D: 6-9days
LS: 8-12 days
kill parasitic worms
destroy Ag-Ab complexes
inactivate some infla. chemicals of allergy - basophil
-
# 20-50
D: 3-7 days
LS: ? (a few hrs to a few days)
release histamine & other mediators of infla.
contain heparin - lymphocyte
-
# 1,500-3,000
D: days to weeks
LS: hrs to years
mount immune response by direct cell attack or via antibodies - monocyte
-
# 100-700
D: 2-3 days
LS: months
phagocytosis
develop into macrophages in tissues - platelets
-
# 250,000-500,000
D: 4-5 days
LS: 5-10 days
seal small tears in blood vessels
instrumental in blood clotting