skin pathology definitions-robbins
Terms
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- Macule
- Circunscribed lession of up to 5 mm in diameter. Flatness, distinguish by surrounding skin by its discoloration
- Path
- Circunscribed lession of more than 5 mm in diameter. Flatness, distinguish by surrounding skin by its discoloration
- Papule
- Elevated dome shaped or flat topped lession 5 mm or less across.
- Plaque
- elevated topped lession, greater than 5 mm across.
- Blister
- vesicle or bulla
- Difference bet pastule, bulla and vesicle
- Vesicle: fluid filled lession less than 5 mm across. Bulla: fluid filled lession > 5 mm across. Pastule:pus filled raised lesion.
- Excoriotic
-
often self induced traumatic
breakage of the epidermis: scratch. - Hyperkeratosis vrs. parakeratosis
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Hyperkeratosis: Thickening of stratum corneum.
Parakeratosis:keratination charact by retention of the nuclei in the stratum corneum. - spongiosis
- intercellular edema of the epidermis.
- lichenification
- thickened and rough skin charact by prominent skin margins; usually the result of repeated rubbing.
- lentiginous
- linear pattern of melanocytes proliferation within the epidermal basal layer.
- vitiligo
- common disorder charact by partial or complete loss of melanocytes within the epidermis.
- lentigo
- common benign localized hyperplasia of melanocytes occurring at all ages but often in infancy and childhood.
- melanocytic nevus (mole)
- any congenital or acquired neoplasm of melanocytes thus it is a misnomer. Important because their recognition is an important model of tumor progresion.
- Dysplastic nevi
- BK moles. tendency to occur in non-sun exposed and sun-exposed body surfaces. Prone to form malignant melanoma.