Hematology - Transfusion Medicine
Terms
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- AB antigens elicit _____ antibodies, causing _____ _____.
- IgM antibodies; intravascular hemolysis
- Group AB ppl are universal _____ because they do not make _____.
- recipients; anti-AB antibodies
- Rh antigens elicit _____, causing _____ _____.
- IgG antibodies; extravascular hemolysis
- What is the Direct Coombs Test?
- Test for autoimmune hemolysis; take patient RBCs and see if agglutinate with Coombs Reagent, anti-human IgG
- What is the Indirect Coombs Test?
- Test for pretransfusion compatibility; take patient's serum and put with known RBC type
- What is used for most transfusions?
- Packed red blood cells
- Fresh frozen plasma contains...
- all clotting factors except platelets.
- What is contained in cryoprecipitate?
- factors VIII, vWF, IX, fibrinogen
- When do you give packed platelets?
- Thrombocytopenic bleeding
- What is the most frequent infection in blood transfusions?
- Hepatitis C