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Bio2401-3A

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All living things are composed of cells, the cell is the basic unit of life.
The Cell Theory
Three Basic parts of Human Cells
Plasma Membrane
Cytoplasm
Nucleus

flexible outer boundary
Plasma Membrane
Contents of the cell minus the Nucleus
Cytoplasm
Control Center
Nucleus
all cells have the same basic parts and some common functions
Generalized Cells/
Composite Cells
He first described cells in 1665
Robert Hooke
He reported all living things are composed of cells.
Matthias Schleiden
Zoology
Theodor Schwann
He proclaimed that cells come from pre-existing cell by cell division
Rudolf Virchow
The plasma membrane seperates two of the body's major fluid compartments known as...
Intracellular Fluid
Extracellular Fluid
Fluid within the cells
Intracellular Fluid
Fluid outside the cells
Extracellular Fluid
Lipids with polar sugar groups on outer membrane surface
glycolipids
increases membrane stability and fluidity
Cholesterol
firmly inserted into the lipid bilayer
integral proteins
loosely attached to the integral proteins
peripheral proteins
Function:
transports proteins, enzymes, or receptors
Integral Proteins
Function:
Provide support on intracellular surface and form part of glycocalyx
Peripheral Proteins
Function of Membrane Protein:
channels or carriers
Transport
Function of Membrane Protein:
Receives signals from hormones
Receptor Proteins
Function of Membrane Proteins:
attach to cytoskeleton (inside cell) and extracellular matrix (outside cell)
Attachement Proteins
Function of Membrane Proteins:
act as a team that catalyzes sequential steps
Enzymatic Proteins
Function of Membrane Proteins:
provide temporary binding sites that guide cell migration
Intercellular Proteins
Function of Membrane Protein:
serve as identification tags that are specifically recognized by other cells
Cell to Cell Recognition Proteins
Prevent fluids and most molecules from moving between cells.
Tight Junctions
"spot welds" that anchor cells together
Desosomes
gaps in adjacent cell membranes that allow passage of materials between cells
Gap Junctions
allows some substances to pass while excluding others
selectively (differentially) permeable
no cellular energy required
passive Process
energy required
active process
nonpolar and lipid soluble substances diffuse directly through the lipid bilayer.
Simple Diffusion
moves through water filled protein channels
channel mediated diffusion
binds to protein carriers in the membrane and is ferried across
carrier mediated diffusion
movement of solvent across a selectively permeable membrane
osmosis
channels that are always open
leakage channels
channels that are controlled by chemical or electrical channels
gated channels
the total concentration of all solute particles in a solution
osmolarity
ability in a solution to cause a cell to shrink or swell
tonicity
same dissolved solute as cell
isotonic
greater solute than cell (shrink)
hypertonic
less solute than cell (swell)
hypotonic

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